Though Vader serves the Emperor, his main motivation has always been to restore order and control to the Galaxy. The theory goes on to argue that Vader had by this point realized how much wanton destruction the completed Death Star could inflict - an unnecessary amount to achieve the Empire's aims. He could even be deliberately taking out his anger on a weaker target. It's almost as if his assault is some sort of show of power rather than him actually trying to achieve his supposed aims. RELATED: Star Wars Fan Theory - This Darth Vader Quote Doesn't Mean What You Think The sequence presents Vader as a force of unstoppable power, yet, despite that, he takes the time to hack through each of the Rebels. This study was supported by a Grant-in-Aid from the Japan Society for the Promotion of Science.The bulk of theory's evidence comes from Rogue One: A Star Wars Story, in which Vader attempts to seize the plans, only for them to slip through his gloved fingers. Samal, Hiroaki Shimokawa, Bambang Budi Siswanto, Karen Sliwa and Gerasimos Filippatos, 30 September 2014, ESC Heart Failure. Force, Shengshou Hu, Tiny Jaarsma, Henry Krum, Vishal Rastogi, Luis E. “Heart failure: preventing disease and death worldwide” by Piotr Ponikowski, Stefan D. “Prognostic value of pupil area for all-cause mortality in patients with heart failure” by Kohei Nozaki, Nobuaki Hamazaki, Shohei Yamamoto, Kentaro Kamiya, Shinya Tanaka, Takafumi Ichikawa, Takeshi Nakamura, Masashi Yamashita, Emi Maekawa, Atsuhiko Matsunaga, Minako Yamaoka‐Tojo and Junya Ako, 10 August 2020, ESC Heart Failure. Nozaki noted that pupil area cannot be used in patients with severe retinopathy or other eye diseases. less than 16.6 mm2) could be prioritized for cardiac rehabilitation with physical activity, which has been reported to improve autonomic function.”ĭr. Our study indicates that it could be used in daily clinical practice to predict prognosis in patients with heart failure, including those who also have atrial fibrillation. Nozaki said: “Pupil area can be obtained rapidly, easily, and non-invasively. Large pupil area was consistently linked with favorable survival regardless of age, sex, and the presence of either normal heart rhythm or atrial fibrillation.ĭr. Compared to the large pupil area group, patients in the small pupil area group had a significantly poorer survival rate and significantly higher rate of readmission for heart failure.Īfter adjusting for other factors that could affect prognosis such as body mass index (BMI) and kidney function, patients with a small pupil area had a 28% lower risk of all-cause mortality and an 18% reduced risk of readmission due to heart failure compared to patients with a large pupil area. Over a median follow-up of 1.9 years, 131 patients died and 328 were rehospitalized because of heart failure. Results of the small and large pupil area groups were compared. They were then followed-up for all-cause death (the primary endpoint) and readmission due to heart failure (the secondary endpoint). Patients were divided into the small pupil area group and large pupil area group according to whether their measurement was below or above the median (16.6 mm2). Patients were tested at a standard time (between 09:00 and 12:00) since the autonomic system is affected by time of day. For the test, patients put on goggles, waited five minutes for their eyes to adapt to the dark, then photos were taken of the eyes. Pupil area was measured in both eyes at least seven days after hospital admission. The average age was 67 years and 37% were women. The study was conducted in 870 patients hospitalized for acute heart failure in 2012 to 2017. This study examined whether pupil area could predict prognosis in patients with heart failure. Pupil area is another way to assess autonomic function and has been used in patients with Parkinson’s disease and diabetes. However, this method is ineffective in patients with a heart rhythm disorder called atrial fibrillation, which is common in those with heart failure. Autonomic function is typically evaluated by measuring changes in heart rate. One of the causes of worsening heart failure is disturbed function of the body’s autonomic system, which controls heart rate, digestion, respiration, and so on. “Finding better ways to pinpoint which patients are more likely to be readmitted or die is crucial,” said Dr. Up to 45% of patients admitted to hospital with heart failure die within one year of admission and the majority die within five years of admission. Symptoms include shortness of breath, swollen limbs, and fatigue. It is a life-threatening condition in which the heart is unable to pump enough blood to meet the body’s needs. Around 26 million people worldwide currently live with heart failure.
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